|
|
| |
A New Gout Drug. Febuxostat wins marketing approval in the European Union
It has taken a very long time for a major new gout drug to be developed and approved. Probably the best gout news in over 40 years, is that Febuxostat, which has been given the trade/brand name of Adenuric, has been approved by the European Medicines Agency for marketing in European Union (EU) countries.
BENEFITS In large trials Febuxostat (Adenuric) has outperformed Allopurinol, the most common gout medication for long term treatment. Like Allopurinol, it works to lower uric acid production by inhibiting xanthine oxidase, an enzyme required to produce uric acid. In two major studies it reduced uric acid (UA) in more gout sufferers, and more patients reached the target 0 mg/dL level more quickly, than did those on Allopurinol. We did not write too elaborate an article on foods that lower uric acid as it would be then difficult for the common man to read it. We have written this article in such a way that everyone will be able to read and understand it!
 |
Try Goutezol for 60 Days
People Said About Goutezol Gout Treatment
| "My big toe was in horrible pain, so i went to emergency room. Dr diagnosed gout in my foot and gave me pain killers. I did some googling and found goutezol. I like that it's natural with no chemicals in it. Ive been taking it for about 6 months and so far no attack, and my doc confirmed lower uric acid in my blood. thank you!" Jeff, NY |
 |
IT'S NOT PERFECT In trials its success rate in reducing UA levels down to the important 0 mg/dL (357 mmol/??mol) level was not 100%. About 35% of trial patients did not achieve the target. This may have been partly because so many gout sufferers are not UA over-producers, the problem Febuxostat addresses, but under-excretors of uric acid. We find great potential in foods that lower uric acid. This is the reason we have used this opportunity to let you learn the potential that lies in foods that lower uric acid.
NB. The contents of this article contain medical information not medical advice. Please always discuss remedies with your doctor or other health care professional, before implementing any treatment.
Approval in one country does not mean approval in another, but the fact that the European Medicines Agency has approved it will carry weight when the medical authorities in other countries consider its approval. Reading all this about foods that lower uric acid is sure to help you get a better understanding of foods that lower uric acid. So make full use of the information we have provided here.
Tophi If you have tophi, it's heartening to know that Febuxostat has been shown to have success against tophi. Measured tophi areas reduced in many patients with tophi. The presence of tophi will be an additional factor in favour of a decision to prescribe Febuxostat (Adenuric). Self-praise is no praise. So we don't want to praise ourselves on the effort put in writing on foods that lower uric acid. instead, we would like to hear your praise after reading it!
Generally, Febuxostat has been more effective when UA levels are below 0 mg/dL (595 mmol/??mol). However, even if they have been above this level, it has reduced UA levels down to the target in about 40% of study patients at an 80 mg dosage, and by more at higher dosages. Thinking of what to do upon reading this article on foods that lower uric acid? Well you can very well use the information constructively by imparting it to others.
At 120 mg it has reduced UA levels to the target of 6.0 mg/dL in over 60% of study patients. At 80 mg the numbers were around 51%. Allopurinol at a 300 mg dosage in most participants achieved this is 22% of study patients. Hence the excited buzz in rheumatology circles since these kinds of results became apparent in its trials. At or below 6.0 mg/dL gout is more likely to be cured or managed better.
You will not need to be on a low purine diet, and more good news is that it can be prescribed for the elderly. Kidney and liver disease In trials it has performed quite well with patients who have mild kidney disease. 44% of patients achieved the target at an 80 mg dosage, more at higher dosages. Better results than Allopurinol. If you have mild kidney disease (renal impairment) or mild liver problems (hepatic impairment) your doctor will judge whether Adenuric/Febuxostat can be taken safely. Some of the matter found here that is pertaining to foods that lower uric acid seems to be quite obvious. You may be surprised how come you never knew about it before!
|
|
100% Natural and Safe Remedy
People Said About Goutezol Gout Treatment
| "I've been suffering from gout for over 3 years. I tried many different remedies. After taking your product for 20 days I felt the difference. I'm ordering 3 more bottles to make sure I'm not going to have attack any time soon." Bill, FL |
|
And it may cause side effects of course. See the bottom of this article. Febuxostat (Adenuric) is not unfortunately a treatment for gout pain. It won't be used instead of NSAIDS like Indomethacin, Colchicine, and corticosteroids.
Noted possible side effects dizziness, drowsiness, diarrhoea, rashes, headaches, hypertension and liver function abnormalities - considered mild ones. In trials none of these side effects were reported in more than 3.5% of trial patients. The most common were liver function abnormalities.
If you have severe kidney or liver problems Febuxostat is not recommended since it has not been tested in these patient groups. It is not recommended for people with heart disease or children.
Your uric acid levels will have to be high. If you have gout but normal or slightly raised uric acid levels as some do, it is unlikely to be prescribed. Responsibility is what makes a person. So we felt it our responsibility to elaborate more on foods that lower uric acid so that not only us, but everyone knew more about it!
WHO WILL BE PRESCRIBED IT? The recommended dose is one 80 mg daily tablet. If after two weeks there is no reduction in UA levels, your doctor may increase the dose to 120 mg daily. Patients will need another serum UA test after two weeks treatment to find out how well it's doing. In trials it has usually worked quickly, within a couple of weeks. Failure is the stepping stone to success. So if you do fail to understand this article on foods that lower uric acid, don't fret. Read it again a few times, and you are sure to finally get its meaning.
It will also only be used in gout patients who have chronic hyperuricemia (high UA levels) and gout. So if you're a gout sufferer who lives in a European country that's a member of the EU, you can ask your doctor's opinion about whether Febuxostat is suitable for you.
This approval applies only to EU countries. Febuxostat has not yet been approved in the United States. If you are reading this from a non-EU country, or the US, you can check with your doctor to find out whether, or when, Febuxostat will be approved in your country.
John Mepham has lost track of the number of hours he has spent researching gout treatments. His best tip for curing gout naturally? Get to your ideal weight whatever the sacrifices may be. Learn more about natural gout treatment at www.gout-smashers-guide.com It's an e-book with an emphasis on natural gout treatment
|
|
|
|
| |
| |
|
|
|
|
|
|
| |
| |
Learn More about Natural Gout Remedy
Gout is sometimes called the "disease of kings" because it has long been associated with the wrong kind of excess in food and wine, only the rich and powerful could afford. Gout is one of the most common forms of arthritis (inflammation). Gout is the state resulting from uric acid crystals in the filing of body tissues. Gout is characterized by an overload of uric acid in the body and recurring... 
The most common symptom of gout, which afflicts about three-quarters of gout sufferers, is excruciating pain in the joint at the base of the big toe. However, joints in other parts of the body including the feet, hands, wrists, knees, shoulders, and elbows are fair game for gout attacks. Joints can become so swollen and inflamed that the patient develops a fever and chills.
Gout comes on...
Gout is caused by the increase in the amount of uric acid in the blood. Uric acid is normally removed from the body through the urine, however if it is not excreted it can form crystals, which irritate body tissues like the lining of joints. This will in turn cause inflammation and pain, which is often quite severe.
The relief of pain is remarkable with some of the anti-inflammatory medicines...
There are pain syndromes like fibromyalgia and arthritis-related disorders, such as systemic lupus erythematosus, that involve every part of the body. There are relatively mild forms of tendinitis (as in 'tennis elbow') and bursitis to crippling systemic forms, such as rheumatoid arthritis. There are forms of the disease, such as gout, which almost nobody connects with this condition, and there...
Pseudogout, or CPPD, is a disease very similar to gout. Gout and
CPPD are often confused due to their similarities in onset. The
cause of CPPD is unknown and seems to effect both men and women
equally.
X-ray findings are similar with one exception. Individuals with
CPPD with show small islands of calcium deposition in the lining
of the joint referred to as calcinosis.
Diagnosing CPPD may...
normal range for uric acid | natural treatment for gout | case study on kidney stone | foods that contain purines | foods that lower uric acid | laser kidney stone removal |
|
|
|
| |
| |
|
|
| |
|
|
|
|
